Solvent selection evaluation tools for an early stage at pharmaceutical process
نویسندگان
چکیده
A first level of a methodology for the selection and evaluation of solvent at an early stage is presented inside a programming tool for its systematic and friendly application. This first level is based on properties and characteristics of solvents for their selection. Different tools are integrated into the program to aid the evaluation of the group of solvents selected. A case study is presented to highlight the most important aspects of the methodology. As a result, this kind of analysis can be useful to determine where the efforts related with solvent selection at an early stage should be aim.
منابع مشابه
Development of systematic procedures for the evaluation of solvent selection at an early stage in pharmaceutical processes
Three levels of evaluation for the selection of solvents have been developed, taking account the lack of information as one of the main characteristics of the problem. Tools to aided the evaluations and able to be applied early in design were identified. The first level is based on system properties analysis. A second level considers the impact of the potential streams to be formed on the syste...
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تاریخ انتشار 2007